What should men take for bv

Or browse all treatments or conditions. Dr Don Grant is The Independent Pharmacy's original online prescriber and has advanced in his role to become the Clinical Advisor, using his wealth of experience to advise on our clinical polices and prescribing guidelines. What is bacterial vaginosis? Bacterial vaginosis symptoms Experiences of bacterial vaginosis vary between sufferers, as most women do not display any symptoms at all. The symptoms of BV include: An unusually large discharge from the vagina The discharge is usually thin and pale, and a greyish-white colour A foul, fishy odour often accompanies the discharge Some women report a burning or itching sensation when they pee or after sex If you are unsure whether or not you have bacterial vaginosis, BV self-testing kits like Canestest can be bought over-the-counter to help you confirm.

Can men catch bacterial vaginosis? Can men spread BV? To help us ensure you recieve the right treatment for you we ask that you complete a short health consultation before your treatment is dispatched straight to you. Treat BV at its source with this vaginal gel. Complete a free consultation today and get fast, discreet home delivery. Written by Andy Boysan Published 28 Nov Bacterial Vaginosis BV.

Sometimes BV will go away on its own. But anyone who experiences symptoms should see a doctor for treatment. In most cases, antibiotics will kill the bacteria quickly, and the symptoms will go away.

People who have had BV are more likely to get the infection again. It is essential to treat the condition every time it occurs. This will reduce the risk of complications, such as other STDs. Bacterial vaginosis is the most common vaginal infection, having affected as many as 1 in 4 women in the U.

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We look at symptoms and…. Thrush is a fungal infection caused by Candida yeasts. There are two types: genital thrush, which, in men, can cause irritation and swelling at the…. Male chlamydial urethritis is a common sexually transmitted infection STI that affects the male urethra. Many people with this STI do not have any….

Can males get bacterial vaginosis? Medically reviewed by Alana Biggers, M. Current treatments for BV are sub-optimal and associated with unacceptably high recurrence rates. Despite not being powered to assess the effect of treatment on recurrence, we observed a low incidence of BV recurrence in a group of women with a past history of BV who were having unprotected sex with a regular partner following dual-partner treatment.

There is ongoing debate concerning the pathogenesis of BV recurrence but epidemiological and recent microbiological data strongly suggest sexual transmission is integral to both recurrent and incident disease.

Our data support the need for high quality studies of male partner treatment with accompanying vaginal, cutaneous penile and urethral microbiota data, an untreated or placebo group and long-term follow-up to define the actual contribution of reinfection and disease persistence to BV recurrence in women.

These data support recent reviews that suggest that combination approaches such as dual partner treatment and biofilm-disrupting agents may are likely to be needed to improve treatment outcomes[ 13 , 14 ].

Each vertical line represents the bacterial composition of one urine specimen. Only the 30 most abundant taxa found in urine specimens are included in the heatmap. A lower Bray-Curtis similarity score indicates the vaginal and penile microbiota of couples is dissimilar.

Comparisons are made between specimens from couples collected before treatment D0 , immediately after treatment at day 8 D8 and three weeks after cessation of treatment at day 28 D Differences in the similarity of bacterial communities of sexual partners compared to non-partners were assessed at each time point using the Wilcoxon signed-rank test. We also thank the participants of the study. Browse Subject Areas? Click through the PLOS taxonomy to find articles in your field.

Abstract Objectives Recurrence following recommended treatment for bacterial vaginosis is unacceptably high. Results Twenty-two couples were recruited. Conclusion Combined oral and topical treatment of male partners of women with BV is acceptable and well tolerated. Introduction Bacterial vaginosis BV is a common condition and is associated with adverse pregnancy outcomes, increased risk of pelvic inflammatory disease, and increased susceptibility to HIV and other sexually transmitted infections STIs [ 1 — 4 ].

Methods Participants, recruitment and intervention Recruitment for this study was conducted from August to February at Melbourne Sexual Health Centre MSHC , Australia, and the sample size was determined by funds available for this pilot. Study procedures Before commencing treatment, women completed a questionnaire recording demographic, behavioural, clinical and contraceptive information. Outcomes Primary outcome. Secondary outcome.

Laboratory methods Nugent scoring and specimen storage. DNA extraction, bacterial load quantification and sequencing. Visualisation of the genital microbiota Using R Studio [V0. Participant recruitment, retention and baseline characteristics Forty-one women were referred to the research nurse, 14 women declined and three were deemed ineligible.

Download: PPT. Table 1. Demographic and behavioural characteristics of couples at baseline. Acceptability and tolerability Of the 16 couples who provided adherence and tolerability data, 14 women received oral metronidazole and two requested vaginal clindamycin; all males received both oral metronidazole and topical clindamycin.

Behavioural practices from baseline to day 28 During the treatment period day 0 to 7 six of 16 couples reported unprotected vaginal sex, one couple reported unprotected anal sex and five couples reported oral sex Table 4. Table 4. Behavioural characteristics of couples during study period. Genital microbiota at baseline Of the 21 couples who provided baseline data, there were 20 vaginal and 21 cutaneous penile baseline specimens available for analysis Fig 2.

Fig 3. Heatmap of bacterial abundance from vaginal specimens collected at baseline, day 8 and day Fig 4. Heatmap of bacterial abundance from penile skin specimens collected at baseline, day 8 and day Effect of dual partner treatment on the vaginal and penile microbiota Using paired comparisons, we investigated the immediate post treatment response day 0 and 8 and sustained post treatment response day 0 and 28 effect of dual partner treatment on the overall composition and diversity of the genital microbiota, as well as the impact of treatment on the prevalence and abundance of key bacterial taxa present in the vagina and penile skin.

Immediate and sustained effect of treatment on the vaginal microbiota. Fig 5. Immediate and sustained effect of dual partner treatment on the composition and diversity of the genital microbiota of females and males. Immediate and sustained effect of treatment on the cutaneous penile microbiota. Effect of treatment on the prevalence and abundance of key BV-associated bacteria in the vaginal microbiota.

Table 5. Prevalence and changes in prevalence of the 30 most abundant taxa in vaginal specimens over the study period. Effect of treatment on the prevalence and abundance of key BV-associated bacteria in the cutaneous penile microbiota. Table 6. Prevalence and changes in prevalence of the 30 most abundant taxa in penile skin specimens over the study period. Effect of treatment on the total bacterial load of the vaginal and penile microbiota. Impact of sexual partnerships on the similarity of vaginal and cutaneous penile microbiota.

Discussion This pilot study aimed to determine whether combined oral and topical antimicrobial treatment of male partners of women with BV was acceptable and well tolerated, and to examine the effect of dual-partner therapy on the vaginal and penile microbiota. Conclusions We report that male partner treatment for BV is acceptable and treatment was tolerable. Supporting information. S1 File. Additional methods and results. S2 File. TREND statement checklist. S3 File. Study protocol. S1 Table. Negative controls analysed.

S2 Table. Potential contaminants removed from OTU table prior to analysis. S3 Table. Proportional abundances of the 30 most abundant taxa in vaginal specimens and cutaneous penile specimens over the study period.

S4 Table. Correlation of specific bacterial taxa between vaginal and cutaneous penile specimens of couples at baseline, day 8 and day S1 Fig.

Heatmap of bacterial abundance from urine specimens collected at baseline, day 8 and day S2 Fig. Comparison of Bray-Curtis Similarity distances between the genital microbiota of sexual partners and non-sexual partners over the study period. References 1. Bacterial vaginosis and disturbances of vaginal flora: association with increased acquisition of HIV. Preventing adverse sequelae of bacterial vaginosis: a public health program and research agenda.

Sex Transm Dis. Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition. J Infect Dis. A cluster analysis of bacterial vaginosis-associated microflora and pelvic inflammatory disease. American journal of epidemiology. Molecular identification of bacteria associated with bacterial vaginosis.

N Engl J Med. Hillier SL. Diagnostic microbiology of bacterial vaginosis. Am J Obstet Gynecol. Vaginal microbiome of reproductive-age women. Bacterial communities in women with bacterial vaginosis: high resolution phylogenetic analyses reveal relationships of microbiota to clinical criteria.

PLoS One. Quantitative PCR assessments of bacterial species in women with and without bacterial vaginosis. J Clin Microbiol. Targeted PCR for detection of vaginal bacteria associated with bacterial vaginosis.

High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence. Long-term follow-up of patients with bacterial vaginosis treated with oral metronidazole and topical clindamycin. Making inroads into improving treatment of bacterial vaginosis—striving for long-term cure.

BMC Infect Dis. Higher-risk behavioral practices associated with bacterial vaginosis compared with vaginal candidiasis. Obstet Gynecol.

Early sexual experiences and risk factors for bacterial vaginosis. Schwebke JR, Desmond R. Risk factors for bacterial vaginosis in women at high risk for sexually transmitted diseases. Incident bacterial vaginosis BV in women who have sex with women is associated with behaviors that suggest sexual transmission of BV.

Clin Infect Dis. Sexual risk factors and bacterial vaginosis: a systematic review and meta-analysis. Risks for acquisition of bacterial vaginosis among women who report sex with women: a cohort study. The TSC will provide trial oversight and advise on scientific design and rigour. The DSMB, in agreement with the TSC, may suggest changes in the conduct of the study should concerns surrounding the safety of patients arise from review of the interim results or aspects of study conduct that warrant modification e.

The HREC may audit the trial at any time. Any identifying or confidential data will be kept in locked cabinets or password protected computer databases, accessible only by named investigators.

All specimens will be de-identified prior to processing. All data will be de-identified and aggregated prior to dissemination in conference abstracts, presentations or publications.

Plain language summaries of the findings will be available on the trial site hosted by MSHC at the conclusion of the trial. The post-treatment recurrence rates for the common vaginal condition, BV, remain unacceptably high. A considerable body of evidence now shows that men carry BV-organisms and may be a reservoir for re-infection. This open-label multicentre pragmatic RCT is designed to assess the impact of concurrent male partner treatment with combined oral metronidazole and topical clindamycin with the current standard of care - female treatment only.

If effective, concurrent partner treatment will provide an adjunctive therapy for women with a regular partner and may provide the first opportunity for high level sustained BV cure. Additionally, if effective, this approach would also result in improved antibiotic stewardship as women would not require repeated courses of antibiotics for recurrence.

This clinical research will be able to be translated to changes to treatment guidelines for BV. The first participant was recruited on 8 April and recruitment is expected to continue to 31 December High global burden and costs of bacterial vaginosis: a systematic review and meta-analysis. Sex Transm Dis. A public health approach to adverse outcomes of pregnancy associated with bacterial vaginosis.

Int J Gynaecol Obstet. PubMed Article Google Scholar. Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infection.

J Infect Dis. Bacterial vaginosis associated with increased risk of female-to-male HIV-1 transmission: a prospective cohort analysis among African couples. PLoS Med.

Genital inflammation and the risk of HIV acquisition in women. Clin Infect Dis. Sexually Transmitted Disease Treatment Guidelines, Google Scholar. The effects of antimicrobial therapy on bacterial vaginosis in non-pregnant women. The Cochrane database of systematic reviews. High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence.

Sexually transmitted infections: challenges ahead. Lancet Infect Dis. Potter J. Should sexual partners of women with bacterial vaginosis receive treatment? Br J Gen Pract. Haemophilus vaginalis vaginitis: a newly defined specific infection previously classified non-specific vaginitis. Am J Obstet Gynecol. Comparison of single-dose vs one-week course of metronidazole for symptomatic bacterial vaginosis.

Bacterial vaginosis: a double-blind randomized trial of the effect of treatment of the sexual partner. Br J Obstet Gynaecol. The effectiveness of single-dose metronidazole therapy for patients and their partners with bacterial vaginosis.

J Fam Pract. Should male consorts of women with bacterial vaginosis be treated? Genitourin Med. A randomized double-blind trial of tinidazole treatment of the sexual partners of females with bacterial vaginosis. Obstet Gynecol. Treatment of male partners and recurrence of bacterial vaginosis: a randomised trial. Mehta SD.

Systematic review of randomized trials of treatment of male sexual Partners for Improved Bacterial Vaginosis Outcomes in women.

Antibiotic treatment for the sexual partners of women with bacterial vaginosis. Cochrane Datab Syst Rev. Recurrence of bacterial vaginosis is significantly associated with posttreatment sexual activities and hormonal contraceptive use.

Combined oral contraceptive pill-exposure alone does not reduce the risk of bacterial vaginosis recurrence in a pilot randomised controlled trial. Sci Rep. Penile microbiota and female partner bacterial vaginosis in Rakai, Uganda. Bacterial communities of the coronal sulcus and distal urethra of adolescent males. PLoS One. Front Cell Infect Microbiol. Characteristics of women and their male sex partners predict bacterial vaginosis among a prospective cohort of Kenyan women with non-optimal vaginal microbiota.

Bacterial communities in penile skin, male urethra, and vaginas of heterosexual couples with and without bacterial vaginosis. Histol Histopathol. PubMed Google Scholar. Microbial diversity of genital ulcer disease in men enrolled in a randomized trial of male circumcision in Kisumu, Kenya.

PloS one. The effects of circumcision on the penis microbiome. The role of male circumcision in the prevention of human papillomavirus and HIV infection. Male circumcision significantly reduces prevalence and load of genital anaerobic bacteria. The effects of male circumcision on female partners' genital tract symptoms and vaginal infections in a randomized trial in Rakai, Uganda.